... The Actual And Physical Conduct Of

... The Actual And Physical Conduct Of An Experiment Must Govern The Statistical Procedure Of Its Interpretation.

No Isolated Experiment, However Significant In Itself, Can Suffice For The Experimental Demonstration Of Any Natural Phenomenon; For The "one Chance In A Million" Will Undoubtedly Occur, With No Less And No More Than Its Appropriate Frequency, However Surprised We May Be That It Should Occur To Us.

The Neutral Zone Of Selective Advantage In The Neighbourhood Of Zero Is Thus So Narrow That Changes In The Environment, And In The Genetic Constitution Of Species, Must Cause This Zone To Be Crossed And Perhaps Recrossed Relatively Rapidly In The Course Of Evolutionary Change, So That Many Possible Gene Substitutions May Have A Fluctuating History Of Advance And Regression Before The Final Balance Of Selective Advantage Is Determined.

Fairly Large Print Is A Real Antidote To Stiff Reading.

To Consult The Statistician After An Experiment Is Finished Is Often Merely To Ask Him To Conduct A Post Mortem Examination. He Can Perhaps Say What The Experiment Died Of.